IRON OVERLOAD IN BETA THALASSEMIA – A Review
نویسندگان
چکیده
Due to improvements in transfusion therapy in beta-thalassemia major patients, transfusional hemosiderosis has now become the major cause of late morbidity and mortality in them. In India and other developing countries, iron chelation therapy is still not strictly adhered to in these children, mostly due to financial constraints. An orally effective and cheap iron chelator is the need of the hour in the treatment of beta-thalassemia major. With the advent of Deferasirox, there is new enthusiasm in this front. This review takes us through the mechanics of iron overload into the various therapies available at our disposal today and those that may be available tomorrow.
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